Article

The <i>Peroxiredoxin 6</i> gene plays a critical role in the homeostatic regulation of fear response

2020-07-10

Abstract excerpt

Peroxiredoxin 6 (PRDX6) is a multifunctional enzyme implicated in redox regulation and expressed in many organs including the brain. It is known to participate in many psychiatric functions, but its role in fear memory is unknown. The present study demonstrates that PRDX6 plays a critical role in the regulation of fear response. Using Prdx6 knockout ( Prdx6 −/− ) mice, we identified that PRDX6 acts as a suppres...

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Literature Corpus work: 23c22aa4-fb81-5b8c-b747-1ed8387e88e6
DOI: 10.1101/2020.07.10.196477

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