Article
A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6.
Journal of lipid research - 1 Apr 2016
Fisher Aron B, Dodia Chandra, Sorokina Elena M, Li Haitao, Zhou Suiping, Raabe Tobias, Feinstein Sheldon I
Abstract excerpt
The phospholipase A2(PLA2) activity of peroxiredoxin (Prdx)6 has important physiological roles in the synthesis of lung surfactant and in the repair of peroxidized cell membranes. These functions require the activity of a lysophospholipid acyl transferase as a critical component of the phospholipid remodeling pathway. We now describe a lysophosphatidylcholine acyl transferase (LPCAT) activity for Prdx6 that...
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