Article
Presenilin Mutation Suppresses Lung Tumorigenesis via Inhibition of Peroxiredoxin 6 Activity and Expression.
Theranostics - 1 Jan 2017
Park Mi Hee, Yun Hyung-Mun, Hwang Chul Ju, Park Sang Ick, Han Sang Bae, Hwang Dae Youn, Yoon Do-Young, Kim Sanghyeon, Hong Jin Tae
Abstract excerpt
Some epidemiological studies suggest an inverse correlation between cancer incidence and Alzheimer's disease (AD). In this study, we demonstrated experimental evidences for this inverse relationship. In the co-expression network analysis using the microarray data and GEO profile of gene expression omnibus data analysis, we showed that the expression of peroxiredoxin 6 (PRDX6), a tumor promoting protein was...
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