Article

Double edged roles of endogenous PRDX6 in ventilator-induced lung injury via modulating oxidative stress and macrophages activation

2024-03-14

Abstract excerpt

<title>Abstract</title> <p>PRDX6 is highly expressed in lung tissues and shows an important biological significance. However, its specific roles in ventilator-induced lung injury (VILI) have not been clearly explored. The present study investigated the roles of endogenous PRDX6 in VILI, focusing on its overall and the iPLA2 function on lung injury, oxidative stress (OS), macrophages activation and polarization. B...

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Literature Corpus work: 01f4d242-28e0-5f80-9497-c948575b072d
DOI: 10.21203/rs.3.rs-3971634/v1

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