Article
Immune reactivity to neurofilaments and dipeptide repeats in ALS progression
2020-02-26
Abstract excerpt
<h4>Objective</h4> To test antibody response and formation of immune-complexes to neurofilaments and dipeptide-repeats, the translational products of the mutated C9orf72 gene, as potential biomarkers for clinical stratification of amyotrophic lateral sclerosis (ALS). <h4>Methods</h4> Using neurofilament protein isoforms plasma expression as reference, antibodies and immune-complexes against neurofilament-light,...
Topics
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- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Genetic Neurodegenerative Diseases
- Neurogenetic and Muscular Disorders Research
- Neurological diseases and metabolism
- Parkinson's Disease Mechanisms and Treatments
- Prion Diseases and Protein Misfolding
- Skin and Cellular Biology Research
Identifiers and source
- Literature Corpus work
- 23b3a1ec-a460-58ef-ada1-833bc5642280
- DOI
- 10.1101/2020.02.25.965236
