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Cellular heterogeneity and plasticity in liver cancer

26 Feb 2021

Abstract excerpt

Hepatocarcinogenesis involves complex genetic and cellular dysregulations which drive the formation of hepatocellular carcinoma (HCC), the predominant form of primary liver cancer, with extensive heterogeneity. In contrast to the broad spectrum of molecularly driven therapies available for defined patient groups in certain cancer types, unfortunately the treatment options for HCC are highly limited. The lack of...

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PMID: 33647386
DOI: 10.1016/j.semcancer.2021.02.015

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