Back to search

Article

Mutations in <i>mfd</i> cause <i>Staphylococcus aureus</i> mucoid hyper-biofilm phenotype in chronic rhinosinusitis

2026-07-01

Abstract excerpt

Chronic Rhinosinusitis (CRS) is a common chronic inflammation of the paranasal sinus mucosa. Staphylococcus aureus contributes to its severity through biofilm formation. In this study, we isolated eight sequential methicillin-resistant S. aureus (MRSA) isolates from a patient with severe CRS over a period of 672 days (T1-T8). The isolates were phenotypically and genomically characterised, and the extracellular b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
234c9114-73ac-51aa-a5bf-b972b0f20524
DOI
10.64898/2026.06.30.735446
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Mutations in <i>mfd</i> cause <i>Staphylococcus aureus</i> mucoid hyper-biofilm phenotype in chronic rhinosinusitisDOI 10.64898/2026.06.30.735446
The Intra-Host Evolutionary Landscape And Pathoadaptation Of Persistent <i>Staphylococcus aureus</i> In Chronic RhinosinusitisSemantic proximity
Isolation and Characterization of Biofilm Formation-Defective Mutants of <i>Staphylococcus aureus</i>Semantic proximity
<i>Staphylococcus aureus</i> biofilm secreted factors cause mucosal damage, mast cell infiltration and goblet cell hyperplasia in a rat rhinosinusitis modelSemantic proximity
Prophage acquisition by <i>Staphylococcus aureus</i> contributes to the expansion of Staphylococcal immune evasionSemantic proximity
The intra-host evolutionary landscape and pathoadaptation of persistent Staphylococcus aureus in chronic rhinosinusitisSemantic proximity
A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune EvasionSemantic proximity
Microbiome complexity and <i>Staphylococcus aureus</i> in chronic rhinosinusitisSemantic proximity
Various mutations in icaR, the repressor of the icaADBC locus, occur in mucoid Staphylococcus aureus isolates recovered from the airways of people with cystic fibrosis.Semantic proximity
Increased carriage of virulence genes mediates enhanced pathogenicity of chronic rhinosinusitis-related S. aureus strainsSemantic proximity
Transcriptional Reprogramming of Staphylococcus aureus in Chronic Rhinosinusitis Reveals a Persistence-Associated Phenotype.Semantic proximity
Assessing the role of cold-shock protein C: A novel regulator of <i>Acinetobacter baumannii</i> biofilm formation and virulenceSemantic proximity
Complete Genome Sequence of a Variant of the Methicillin-Resistant Staphylococcus aureus ST239 Lineage, Strain BMB9393, Displaying Superior Ability To Accumulate <i>ica</i> -Independent BiofilmSemantic proximity
Select a neighboring publication to make it the new centre.