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Article

Microbiome complexity and <i>Staphylococcus aureus</i> in chronic rhinosinusitis

17 Jan 2012

Abstract excerpt

OBJECTIVES/HYPOTHESIS: The aim of this study was to compare microbiological culture-based and culture-independent (16S rRNA gene sequencing) methodologies for pathogen identification in chronic rhinosinusitis (CRS) patients. We hypothesized that bacterial culture and DNA sequencing would yield largely concurrent results, although sequencing would detect greater bacterial diversity, and the sinonasal microbiomes...

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PMID: 22253013
DOI: 10.1002/lary.22398

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