Article
New germline mutations in BRCA1, ATM, MUTYH, and RAD51D genes in Tuvans early-onset breast cancer patients.
Experimental oncology - 1 Mar 2021
Gervas P, Molokov A, Ivanova A, Panferova Ye, Kiselev A, Chernyshova A, Pisareva L, Choynzonov E, Cherdyntseva N
Abstract excerpt
BACKGROUND: In Russia, more than 50,000 women are diagnosed with breast cancer (BC) every year. Russia is a multinational country - about 200 ethnic groups live on its territory. Khakass, Buryats, Tuvans and other ethnic groups show higher rate of increase in BC incidence and a younger age of first diagnosed BC compared to Caucasian ethnicities. We focused on Tuvan ethnic group to find specific genetic...
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