Article

Adipocyte-Derived Serpina3c Protects Against High-Fat Diet-Related Arterial Remodeling by Inhibiting ADAMTS4 Activity

2026-01-12

Abstract excerpt

<title>Abstract</title> <p>Obesity is closely associated with arterial stiffening and pathological vascular remodeling, yet its key molecular mechanisms remain incompletely understood. The endocrine function of adipocytes reveals the significance in regulating vascular diseases. This study investigated the adipocyte-derived serine protease inhibitor A3c (Serpina3c) in regulating vascular extracellular matrix (ECM...

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Literature Corpus work: 23161844-4a95-5353-bd3a-acb3e130b885
DOI: 10.21203/rs.3.rs-8511069/v1

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Adipocyte-Derived Serpina3c Protects Against High-Fat Diet-Related Arterial Remodeling by Inhibiting ADAMTS4 ActivityDOI 10.21203/rs.3.rs-8511069/v1Read

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