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Decoupling individual host response and immune cell engager cytotoxic potency

2024-06-25

Abstract excerpt

Immune cell engagers are molecular agents, usually antibody-based constructs, engineered to recruit immune cells against cancer cells and kill them. They represent a versatile and powerful tool for cancer immunotherapy. Despite the multiplication of new engagers tested and accepted in the clinics, how molecular and cellular parameters influence their action is poorly understood. In particular, disentangling the re...

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Identifiers and source

Literature Corpus work
22f19b4c-ba48-5592-9ee7-874788b624a4
DOI
10.1101/2024.06.22.600188
Open publication

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Decoupling individual host response and immune cell engager cytotoxic potencyDOI 10.1101/2024.06.22.600188
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