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Type 2 diabetes amplifies environmental Pb toxicity and intergenerational risk

2026-02-23

Abstract excerpt

Type 2 diabetes (T2D) and environmental lead (Pb) exposure intersect as prevalent global health challenges. Prior studies report elevated blood Pb in T2D, but the underlying mechanism and directionality remain unresolved. Here we show that T2D fundamentally alters Pb toxicokinetics, converting otherwise modest exposure into progressive organ injury and heritable risk. In a human cohort, elevated blood Pb in T2D sp...

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Literature Corpus work
22d36bc4-f3eb-5860-a56e-4af268db7ad7
DOI
10.64898/2026.02.21.707175
Open publication

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Type 2 diabetes amplifies environmental Pb toxicity and intergenerational riskDOI 10.64898/2026.02.21.707175
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