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Circulating organochlorine pesticide levels, genetic predisposition and the risk of incident type 2 diabetes.

Environmental pollution (Barking, Essex : 1987) - 15 Nov 2023

Jia Chengyong, Zhang Shiyang, Cheng Xu, Li Peiwen, An Jun, Zhang Xin, Li Wending, Xu Yali, Yang Handong, Jing Tao, Guo Huan, He Meian

Abstract excerpt

Persistent organochlorine pesticide (OCP) has been associated with type 2 diabetes (T2D), and genetic polymorphism might modify such an association. However, prospective evidence remains scarce. We conducted a nested case-control study comprising 1006 incident diabetic cases and 1006 matched non-diabetic controls [sex and age (±5 years)] from 2008 to 2013 (mean follow-up period: ∼4.6 years) based on the...

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PMID: 37717893
DOI: 10.1016/j.envpol.2023.122541

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