Article
Plasma metals, genetic risk, and rapid kidney function decline among type 2 diabetes.
The Science of the total environment - 10 Oct 2024
Wang Ruixin, Cheng Xu, Long Tengfei, Jia Chengyong, Xu Yali, Wei Yue, Zhang Ying, He Xiangjing, He Meian
Abstract excerpt
BACKGROUND: Rapid kidney function decline (RKFD) is a main clinical feature of early chronic kidney disease (CKD) in type 2 diabetes (T2D). Environmental and genetic factors influencing RKFD remain inadequately elucidated. OBJECTIVES: This study aimed to examine the associations of metals with RKFD among T2D and to further investigate the effect of metal mixtures on RKFD with the modifying effect of genetic...
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