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Longitudinal impact of different treatment sequences of second-generation antipsychotics on metabolic outcomes: a study using targeted maximum likelihood estimation

2024-10-27

Abstract excerpt

<h4>Background</h4> Second-generation antipsychotics (SGAs) cause metabolic side-effects. However, patients’ metabolic profiles were influenced by many time-invariant and time-varying confounders. Real-world evidence on the long-term, dynamic effects of SGAs (e.g. different treatment sequences) is limited. We employed advanced causal inference methods to evaluate metabolic impact of SGAs in a naturalistic cohort....

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Literature Corpus work
228d1c01-c6c2-5f7c-9459-7d2d983aa395
DOI
10.1101/2024.10.25.24315949
Open publication

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Longitudinal impact of different treatment sequences of second-generation antipsychotics on metabolic outcomes: a study using targeted maximum likelihood estimationDOI 10.1101/2024.10.25.24315949
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