Pharmacogenetic study of second-generation antipsychotic long-term treatment metabolic side effects (the SLiM Study): rationale, objectives, design and sample description.

doi:10.1016/j.rpsm.2014.05.004

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Article

Pharmacogenetic study of second-generation antipsychotic long-term treatment metabolic side effects (the SLiM Study): rationale, objectives, design and sample description.

Revista de psiquiatria y salud mental - 1 Jan 2000

Pina-Camacho Laura, Díaz-Caneja Covadonga M, Saiz Pilar A, Bobes Julio, Corripio Iluminada, Grasa Eva, Rodriguez-Jimenez Roberto, Fernández Miryam, Sanjuán Julio, García-López Aurelio, Tapia-Casellas Cecilia, Álvarez-Blázquez María, Fraguas David, Mitjans Marina, Arias Bárbara, Arango Celso

Abstract excerpt

AIM: Weight gain is an important and common side effect of second generation antipsychotics (SGAs). Furthermore, these drugs can induce other side effects associated with higher cardiovascular morbidity and mortality, such as insulin resistance, diabetes or metabolic syndrome. Preliminary studies show that inter-individual genetic differences produce varying degrees of vulnerability to the different SGA-induced...

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PMID: 25440735
DOI: 10.1016/j.rpsm.2014.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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