Article

<i>In vivo</i> discovery of RNA proximal proteins in human cells via proximity-dependent biotinylation

2020-02-28

Abstract excerpt

RNA molecules function as messengers or noncoding adaptor molecules, structural components, and regulators of genome organization and gene expression. Their roles and regulation are mediated by other molecules they interact with, especially RNA binding proteins (RBPs). Here we report RNA proximity labeling (RPL), an RNA-centric method based on fusion of an endonuclease-deficient Type VI CRISPR-Cas protein (dCas13b...

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Literature Corpus work: 22506808-270b-5f4e-8061-661028cf3f2a
DOI: 10.1101/2020.02.28.970442

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