Article

Drug resistance in recurrent and metastatic Ewing sarcoma

2021-10-20

Abstract excerpt

Survival of patients with recurrent and metastatic Ewing sarcoma (ES) has not markedly improved in the last 40 years; the main reason for the poor prognosis of these patients is drug resistance. However, intrinsic and acquired resistance may occur in response to both traditional chemotherapy and targeted drugs. These complex mechanisms plausibly include instability of the genetic material, enhanced drug efflux and...

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Literature Corpus work: 223f4e12-dc4d-508d-a0f2-bb7e80180c78
DOI: 10.22541/au.163476822.21319119/v1

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