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Harnessing ferroptosis for precision oncology: challenges and prospects

23 Feb 2025

Abstract excerpt

The discovery of diverse molecular mechanisms of regulated cell death has opened new avenues for cancer therapy. Ferroptosis, a unique form of cell death driven by iron-catalyzed peroxidation of membrane phospholipids, holds particular promise for targeting resistant cancer types. This review critically examines current literature on ferroptosis, focusing on its defining features and therapeutic potential. We...

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PMID: 39988655
DOI: 10.1186/s12915-025-02154-6

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