Article

Host tRNA modifications drive efficient translation of influenza A virus genome and impact host antiviral stress responses

2026-04-22

Abstract excerpt

Influenza A virus (IAV), as all other viruses, is completely dependent on the host translation machinery components, including host transfer RNAs (tRNAs), to effectively decode its genome. However, while the human genome is biased towards cytosine (C) and guanosine (G)-ending codons, the IAV genome is skewed towards adenine (A) and uridine (U)-ending codons. Nevertheless, translation of IAV’s RNA genome is highly...

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Literature Corpus work: 21ec2bfe-1f99-595c-ab8f-88ad25d6da1a
DOI: 10.64898/2026.04.21.719891

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