Article

Transcriptomically unique endolysosomal and homeostatic microglia populations in Alzheimer’s disease and aged human brain

2021-10-26

Abstract excerpt

Microglia contribute to Alzheimer’s Disease (AD) progression and are candidate therapeutic targets. Human microglia exhibit an array of transcriptional phenotypes implying that accurate manipulation of microglial function will require clarity of their molecular states and context dependent regulation. To increase the number of microglia analyzed per subject we employed fluorescence activated nuclei sorting prior t...

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Literature Corpus work: 21eb3399-e4e3-5175-aeee-d15414a13de9
DOI: 10.1101/2021.10.25.465802

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