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Article

Clinical Germline Testing Results of Men With Prostate Cancer: Patient-Level Factors and Implications of NCCN Guideline Expansion.

JCO precision oncology - 1 Jan 2021

Greenberg Samantha E, Hunt Trevor C, Ambrose Jacob P, Lowrance William T, Dechet Christopher B, O'Neil Brock B, Tward Jonathan D

Abstract excerpt

Germline likely pathogenic or pathogenic variants (PVs) have been identified in up to 17% of men with prostate cancer (PC) and may drive disease severity or be targetable by novel therapies. National Comprehensive Cancer Network (NCCN) guidelines encouraging germline testing in metastatic PC were recently expanded to include all men with high-risk, very high-risk, or regional PC. Our aim was to assess the impact...

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Identifiers

PMID: 34250421
DOI: 10.1200/PO.20.00432
PMCID: PMC8232879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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