Article

<i>Shigella</i> induces epigenetic reprogramming of zebrafish neutrophils

2022-11-04

Abstract excerpt

<h4>SUMMARY</h4> Trained immunity is a long-term memory of innate immune cells, generating an improved response upon re-infection. Shigella is an important human pathogen and inflammatory paradigm for which there is no effective vaccine. Using zebrafish larvae we demonstrate that after Shigella priming neutrophils are more efficient at bacterial clearance. We observe that Shigella -induced protection is non-sp...

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Literature Corpus work: 21b20c17-7f8f-5793-8a89-73f422cb40b6
DOI: 10.1101/2022.11.03.515069

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