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Enhanced virulence and stress tolerance are signatures of epidemiologically successful <i>Shigella sonnei</i>

2025-02-05

Abstract excerpt

Shigellosis is a leading cause of diarrhoeal deaths worldwide, with Shigella sonnei increasingly implicated as a dominant agent. S. sonnei is divided into five monophyletic lineages all sharing a single O-antigen, yet most contemporary infections are caused by just a few clonal sub-lineages within globally dominant Lineage 3 that are quite distinct from the widely used Lineage 2 laboratory strain 53G. Factors un...

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Identifiers and source

Literature Corpus work
ecec61a8-b58a-55ec-9cd6-58e533d38006
DOI
10.1101/2025.02.05.636615
Open publication

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