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Trained immunity and host‐pathogen interactions

17 Sept 2020

Abstract excerpt

Infectious diseases are a leading cause of death worldwide with over 8 million fatalities accounted for in 2016. Solicitation of host immune defenses by vaccination is the treatment of choice to prevent these infections. It has long been thought that vaccine immunity was solely mediated by the adaptive immune system. However, over the past decade, numerous studies have shown that innate immune cells can also...

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PMID: 32902895
DOI: 10.1111/cmi.13261

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