Article

Oligogenic heterozygous inheritance of sperm abnormalities in mouse

2021-11-16

Abstract excerpt

<h4>ABSTRACT</h4> Male infertility is an important health concern that is expected to have a major genetic etiology. Although high-throughput sequencing has linked gene defects to more than 50% of rare and severe sperm anomalies, less than 20% of common and moderate forms are explained. We hypothesized that this low success rate could at least be partly due to oligogenic defects – the accumulation of several rare...

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Literature Corpus work: 21a9ef62-2088-5345-846d-b93e9c3f8828
DOI: 10.1101/2021.11.15.468601

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