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Article

Molecular basis of P[6] and P[8] major human rotavirus VP8* domain interactions with histo-blood group antigens

2019-01-04

Abstract excerpt

Initial cell attachment of rotavirus (RV) to specific cell surface glycans, which is the essential first step in RV infection, is mediated by the VP8* domain of the spike protein VP4. Recently, human histo-blood group antigens (HBGAs) have been identified as ligands or receptors for human RV strains. RV strains in the P[4] and P[8] genotypes of the P[II] genogroup share common recognition of the Lewis b and H type...

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Literature Corpus work
219c55c7-23bf-57d1-9269-d287cb8bac04
DOI
10.1101/512301
Open publication

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Molecular basis of P[6] and P[8] major human rotavirus VP8* domain interactions with histo-blood group antigensDOI 10.1101/512301
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