Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s.

Journal of virology - 15 Jul 2018

Sun Xiaoman, Li Dandi, Qi Jianxun, Chai Wengang, Wang Luyao, Wang Lihong, Peng Ruchao, Wang Han, Zhang Qing, Pang Lili, Kong Xiangyu, Wang Hong, Jin Miao, Gao George F, Duan Zhaojun

Abstract excerpt

Rotaviruses (RVs), which cause severe gastroenteritis in infants and children, recognize glycan ligands in a genotype-dependent manner via the distal VP8* head of the spike protein VP4. However, the glycan binding mechanisms remain elusive for the P[II] genogroup RVs, including the widely prevalent human RVs (P[8], P[4], and P[6]) and a rare P[19] RV. In this study, we characterized the glycan binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crystallography, X-Ray
Share to Host Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polysaccharides

Share to RNA-Binding Proteins

Share to Rotavirus

Share to Rotavirus Infections

Share to Sequence Homology

Share to Viral Nonstructural Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 29720519
DOI: 10.1128/JVI.00538-18
PMCID: PMC6026740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s.PMID 29720519Read ↗

Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.Semantic proximity Read ↗

Functional and Structural Characterization of P[19] Rotavirus VP8* Interaction with Histo-blood Group Antigens.Semantic proximity Read ↗

Glycan Specificity of P[19] Rotavirus and Comparison with Those of Related P Genotypes.Semantic proximity Read ↗

Structural Basis of Glycan Recognition of RotavirusSemantic proximity Read ↗

Molecular basis of P[6] and P[8] major human rotavirus VP8* domain interactions with histo-blood group antigensSemantic proximity Read ↗

Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigensSemantic proximity Read ↗

Rotavirus VP8*: Phylogeny, Host Range, and Interaction with Histo-Blood Group AntigensSemantic proximity Read ↗

Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigensSemantic proximity Read ↗

Histo-blood group antigens as divergent factors of groups A and C rotaviruses circulating in humans and different animal species.Semantic proximity Read ↗

Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigensSemantic proximity Read ↗

Glycan recognition in globally dominant human rotaviruses.Semantic proximity Read ↗

Diversity in Rotavirus–Host Glycan Interactions: A “Sweet” SpectrumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.