Article

Mutant alleles differentially shape cattle complex traits and fitness

2021-04-19

Abstract excerpt

Classical mutant alleles (MAs), with large effects on phenotype, tend to be deleterious to traits and fitness. Is this the case for mutations with small effects? We infer MAs for 8 million sequence variants in 113k cattle and quantify the effects of MA on 37 complex traits. Heterozygosity for variants at genomic sites conserved across 100 vertebrates increase fertility, stature, and milk production, positively ass...

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Literature Corpus work: 215ee1f4-90f4-5284-bda1-e2e5ea95a545
DOI: 10.1101/2021.04.19.440546

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