Article

Salvianolic acid B alleviates ovarian ageing and fibrosis to restore fertility via dual modulation of the TIMP1/MMP13 interaction

2026-05-13

Abstract excerpt

Abstract Age-related infertility remains a major reproductive challenge, with ovarian ageing increasingly associated with progressive tissue fibrosis. In this study, salvianolic acid B (SALB) was identified as a novel bioactive compound capable of ameliorating ovarian senescence. In vitro, SALB effectively inhibited TGFβ1 -induced myofibroblast activation and extracellular matrix (ECM) accumulation. In vivo admini...

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Literature Corpus work: 21517589-a7ba-5159-88b7-1ef2131c45fe
DOI: 10.22541/authorea.15003281/v1

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Salvianolic acid B alleviates ovarian ageing and fibrosis to restore fertility via dual modulation of the TIMP1/MMP13 interactionDOI 10.22541/authorea.15003281/v1Read

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