Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accelerated Ovarian Aging in the Absence of the Transcription Regulator TAF4B in Mice1

15 Aug 2009

Abstract excerpt

The mammalian ovary is unique in that its reproductive life span is limited by oocyte quantity and quality. Oocytes are recruited from a finite pool of primordial follicles that are usually exhausted from the ovary during midadult life. If regulation of this pool is perturbed, the reproductive capacity of the ovary is compromised. TAF4B is a gonad-enriched subunit of the TFIID complex required for female...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19684329
DOI: 10.1095/biolreprod.109.077495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accelerated Ovarian Aging in the Absence of the Transcription Regulator TAF4B in Mice1PMID 19684329Read ↗

TAF4b Regulates Oocyte-Specific Genes Essential for MeiosisSemantic proximity Read ↗

A single-cell atlas of the aging mouse ovarySemantic proximity Read ↗

A single-cell atlas of the aging murine ovarySemantic proximity Read ↗

Tet1 Deficiency Leads to Premature Ovarian FailureSemantic proximity Read ↗

Aging of Oocyte, Ovary, and Human ReproductionSemantic proximity Read ↗

Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.Semantic proximity Read ↗

Genomewide Discovery and Classification of Candidate Ovarian Fertility Genes in the MouseSemantic proximity Read ↗

Temporal transcriptomic landscape of postnatal mouse ovaries reveals dynamic gene signatures associated with ovarian agingSemantic proximity Read ↗

Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctionsSemantic proximity Read ↗

FIGLA, a Basic Helix-Loop-Helix Transcription Factor, Balances Sexually Dimorphic Gene Expression in Postnatal OocytesSemantic proximity Read ↗

Single‐oocyte transcriptome analysis reveals aging‐associated effects influenced by life stage and calorie restrictionSemantic proximity Read ↗

PRC1-mediated epigenetic programming is required to generate the ovarian reserveSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.