Article

A cell line model for the study of CD4-negative HIV-1 infection and latent virus reservoirs

2026-07-01

Abstract excerpt

<h4>ABSTRACT</h4> Although controversial, limited publications support the notion that HIV-1 can infect CD4-negative cells. The objective of this study was to provide a comprehensive investigation of a universally available CD4-negative cell line model system that can be infected with X4 and R5 HIV-1 to generate integrated proviral DNA and serve to study latent viral reservoirs. The reason that HIV-1 infection of...

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Literature Corpus work: 2143e6de-98ff-5683-8b56-b1c0948812e4
DOI: 10.64898/2026.06.26.734695

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