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Development of an HIV reporter virus that identifies latently infected CD4+ T cells

1 Jun 2022

Abstract excerpt

There is no cure for HIV infection, as the virus establishes a latent reservoir, which escapes highly active antiretroviral treatments. One major obstacle is the difficulty identifying cells that harbor latent proviruses. We devised a single-round viral vector that carries a series of versatile reporter molecules that are expressed in an LTR-dependent or LTR-independent manner and make it possible to accurately...

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PMID: 35784650
DOI: 10.1016/j.crmeth.2022.100238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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