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T-cell Line for HIV Drug Screening Using EGFP as a Quantitative Marker of HIV-1 Replication

1 Jan 2006

Abstract excerpt

The rapid increase of viral strains that are resistant to the currently available antiretroviral drugs is a threat to the success of current human immunodeficiency virus type 1 (HIV-1) treatment and emphasizes the importance of developing novel anti-HIV-1 compounds. To improve the current abilities to screen for novel HIV-1 inhibitors, here we introduce a T-cell-based reporter cell line (JLTRG-RS) that expresses...

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PMID: 16454046
DOI: 10.2144/000112072

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