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Long-read sequencing to interrogate strain-level variation among adherent-invasive <i>Escherichia coli</i> isolated from human intestinal tissue

2020-03-10

Abstract excerpt

Adherent-invasive Escherichia coli (AIEC) is a pathovar linked to inflammatory bowel diseases (IBD), especially Crohn’s disease, and colorectal cancer. AIEC are genetically diverse, and in the absence of a universal molecular signature, are defined by in vitro functional attributes. The relative ability of difference AIEC strains to colonize, persist, and induce inflammation in an IBD-susceptible host is unresol...

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Literature Corpus work
2140b933-f48e-5f97-ba44-2ed8ad9c48c5
DOI
10.1101/2020.03.10.985440
Open publication

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Long-read sequencing to interrogate strain-level variation among adherent-invasive <i>Escherichia coli</i> isolated from human intestinal tissueDOI 10.1101/2020.03.10.985440
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