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Article

Genetic and Microbial Analysis of Invasiveness for Escherichia coli Strains Associated With Inflammatory Bowel Disease.

Cellular and molecular gastroenterology and hepatology - 1 Jan 2025

Kim Jungyeon, Zhang Jing, Kinch Lisa, Shen Jinhui, Field Sydney, Khan Shahanshah, Klapproth Jan-Michael, Forsberg Kevin J, Harris-Tryon Tamia, Orth Kim, Cong Qian, Ni Josephine

Abstract excerpt

BACKGROUND & AIMS: The adherent-invasive Escherichia coli (AIEC) pathotype is implicated in inflammatory bowel disease (IBD) pathogenesis. AIEC strains are currently defined by phenotypic measurement of their pathogenicity, including invasion of epithelial cells. This broad definition, combined with the genetic diversity of AIEC across patients with IBD, has complicated the identification of virulence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40437706
DOI: 10.1016/j.jcmgh.2024.101451
PMCID: PMC11879602

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