Article

Apathy and Affective Symptoms Associated with Elevated Alzheimer’s Disease Biomarkers

2024-11-07

Abstract excerpt

<h4>Importance</h4> While apathy and affective neuropsychiatric symptoms (NPS) are common in the clinical spectrum of Alzheimer’s disease (AD), their neurobiological correlates remain unclear. <h4>Objective</h4> To longitudinally examine plasma markers of neurodegeneration (neurofilament light chain; NfL) and tau pathology (phosphorylated at threonine 181; p-tau181) and their associations with apathy and affective...

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Literature Corpus work: 20edd842-a024-5693-9890-d92848a594fe
DOI: 10.1101/2024.11.06.24316730

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