Article
Toward Precision Neuropsychiatry of Dementia: Neuropsychiatric Symptoms as Multidimensional Clinical Phenotypes.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Sept 2026
Shinagawa Shunichiro, Nagata Tomoyuki
Abstract excerpt
Neuropsychiatric symptoms (NPS) are the most clinically consequential manifestations of dementia, yet they are frequently underestimated as secondary behavioural complications. This review introduces a precision neuropsychiatry framework that conceptualises NPS-including apathy, agitation, psychosis, depression, and sleep disturbances-as multidimensional clinical phenotypes. These phenotypes bridge...
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