Apathy phenotypes in depression and dementia: A latent profile analysis.

doi:10.1016/j.comppsych.2026.152741

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Article

Apathy phenotypes in depression and dementia: A latent profile analysis.

Comprehensive psychiatry - 1 Sept 2026

de Filippis Renato, Aloi Matteo, Carbone Elvira Anna, Pascucci Elena, Luppino Domenico Luigi, Scaramuzzino Andrea, Liparota Gaspare, Segura-Garcia Cristina, Gareri Pietro, De Fazio Pasquale

Abstract excerpt

INTRODUCTION: Apathy is a frequent psychopathological construct, recently described as a multidimensional concept involving executive, initiation, and emotional features, and is observed in both psychiatric and neurodegenerative disorders. We aimed to identify latent apathy profiles in major depressive disorder (MDD) and Major Neurocognitive Disorder (MND) groups using the Dimensional Apathy Scale - Italian...

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Topics

Humans
Apathy
Female
Male
Aged
Major Depressive Disorder

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Dementia

Phenotype

Executive Function

Quality of Life

Latent Class Analysis

Psychiatric Status Rating Scales

Source

Open in PubMed

Identifiers

PMID: 42607410
DOI: 10.1016/j.comppsych.2026.152741

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