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Article

Estrous cycle stage critically affects 21-gene recurrence scores in Mmtv-Pymt mouse mammary tumours

2020-07-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The Oncotype DX 21-gene Recurrence Score is predictive of adjuvant chemotherapy benefit for women with early-stage, estrogen receptor (ER)-positive, HER2-negative breast cancer. In premenopausal women, fluctuations in estrogen and progesterone during the menstrual cycle impact gene expression in hormone-responsive cancers. However, the extent to which menstrual...

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Literature Corpus work
20a3f124-d718-5ada-b30c-ef577ba2b2f2
DOI
10.21203/rs.3.rs-44909/v1
Open publication

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Estrous cycle stage critically affects 21-gene recurrence scores in Mmtv-Pymt mouse mammary tumoursDOI 10.21203/rs.3.rs-44909/v1
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