Article

Subtype-specific circadian clock dysregulation modulates breast cancer biology, invasiveness, and prognosis

2023-05-19

Abstract excerpt

<h4>Summary</h4> Studies in shift workers and model organisms link circadian disruption to breast cancer. However, molecular rhythms in non-cancerous and cancerous human breast tissues are largely unknown. We reconstructed rhythms informatically, integrating locally collected, time-stamped biopsies with public datasets. For non-cancerous tissue, the inferred order of core-circadian genes matches established physi...

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Identifiers and source

Literature Corpus work: 7ec03826-fb78-5133-9e18-7108411516c7
DOI: 10.1101/2023.05.17.540386

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