Article

Human Non-hypertrophic Nonunion Tissue Contains Osteoblast Lineage Cells and E-BMP-2 Activates Osteogenic and Chondrogenic Differentiation

2022-02-25

Abstract excerpt

<h4>Background: </h4> Nonunions without hypertrophic callus formation has been identified based on X-ray findings, and we have defined it as non-hypertrophic nonunion. Bone morphogenetic protein-2 (BMP-2) is a well-known growth factor for bone regeneration, and Escherichia coli -derived BMP-2 (E-BMP-2) is considered a low-cost alternative to currently available products for humans. In this in vitro study, we exami...

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Literature Corpus work: 20a1bffb-27ff-5076-a376-ca12a6169ba1
DOI: 10.21203/rs.3.rs-1381413/v1

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