Article
Defective Proliferation and Osteogenic Potential with Altered Immunoregulatory phenotype of Native Bone marrow-Multipotential Stromal Cells in Atrophic Fracture Non-Union.
Scientific reports - 22 Nov 2019
El-Jawhari Jehan J, Kleftouris George, El-Sherbiny Yasser, Saleeb Hany, West Robert M, Jones Elena, Giannoudis Peter V
Abstract excerpt
Bone marrow-Multipotential stromal cells (BM-MSCs) are increasingly used to treat complicated fracture healing e.g., non-union. Though, the quality of these autologous cells is not well characterized. We aimed to evaluate bone healing-related capacities of non-union BM-MSCs. Iliac crest-BM was aspirated from long-bone fracture patients with normal healing (U) or non-united (NU). Uncultured (native)...
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