Article

Silencing Smad7 Potentiates BMP2-induced Chondrogenic Differentiation and Inhibits Endochondral Ossification in Human Synovial Derived Mesenchymal Stem Cells

2020-10-28

Abstract excerpt

<title>Abstract</title> <p>Background: Cartilage injuries pose formidable challenges for effective clinical management. Autologous stem cell-based therapies and transgene-enhanced cartilage tissue engineering may open new avenues for the treatment of cartilage injuries. Bone morphogenetic protein 2 (BMP2) is a promising chondrogenic growth factors for transgene-enhanced cartilage tissue engineering. However the B...

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Literature Corpus work: 1070460b-3843-564f-aed8-d4ea9972c38a
DOI: 10.21203/rs.3.rs-96609/v1

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