Article

Integrating Genome-wide and Epigenome-wide Associations for Antipsychotic Induced Extrapyramidal Side Effects

2025-02-28

Abstract excerpt

<h4>Background and Hypothesis</h4> Antipsychotic medications are the first-line treatment for schizophrenia. However, around 40% of people with schizophrenia who are treated with antipsychotics could develop extrapyramidal side-effects (EPSE) including: 1) Dyskinesias, 2) Parkinsonism, 3) Akathisia, and 4) Dystonia. <h4>Study Design</h4> We conducted Genome-wide association (GWAS) and Epigenome-wide association (E...

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Literature Corpus work: 206bc2f4-a769-53a7-ac43-e62d4d3f92dc
DOI: 10.1101/2025.02.27.25323006

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