Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

13 Apr 2023

Abstract excerpt

The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by dissecting both cell lineage and cell fate transitions using single-cell transcriptomic and genetic alteration data from patients with different subtypes of thyroid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioinformatics and Genomic Networks
Share to Ferroptosis and cancer prognosis
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37053016
DOI: 10.1172/jci169653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomicsPMID 37053016Read ↗

Mutation-specific dynamics of dedifferentiation trajectories and tumor-stromal interactions in thyroid cancer.Semantic proximity Read ↗

Transcriptome of Anaplastic Thyroid Cancer Reveals Two Molecular Subtypes with Distinct Tumor Microenvironment and PrognosisSemantic proximity Read ↗

An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulationsSemantic proximity Read ↗

Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinomaSemantic proximity Read ↗

Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers.Semantic proximity Read ↗

Spatial Transcriptomics Reveals Transcriptomic and Immune Microenvironment Reprogramming during Thyroid Carcinoma DedifferentiationSemantic proximity Read ↗

Anaplastic transformation of thyroid cancer: review of clinical, pathologic, and molecular evidence provides new insights into disease biology and future therapy.Semantic proximity Read ↗

Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers.Semantic proximity Read ↗

The Genomic Landscape of Thyroid Cancer Tumourigenesis and Implications for Immunotherapy.Semantic proximity Read ↗

Idiosyncratic and generic single nuclei and spatial transcriptional patterns in papillary and anaplastic thyroid cancersSemantic proximity Read ↗

C/EBPβ Drives Anaplastic Thyroid Cancer Dedifferentiation and Radioiodine Resistance via IL-6/JAK/STAT and EMT ActivationSemantic proximity Read ↗

The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.