Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product

2 Jan 2025

Abstract excerpt

Circulating Tumor Cells (CTCs) in blood encompass DNA, RNA, and protein biomarkers, but clinical utility is limited by their rarity. To enable tumor epitope-agnostic interrogation of large blood volumes, we developed a high-throughput microfluidic device, depleting hematopoietic cells through high-flow channels and force-amplifying magnetic lenses. Here, we apply this technology to analyze patient-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39746954
DOI: 10.1038/s41467-024-55140-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis productPMID 39746954Read ↗

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis productSemantic proximity Read ↗

Development and clinical validation of a microfluidic-based platform for CTC enrichment and downstream molecular analysisSemantic proximity Read ↗

Liquid biopsy: current technology and clinical applicationsSemantic proximity Read ↗

A Microfluidic Chip for Efficient Circulating Tumor Cells Enrichment, Screening, and Single‐Cell RNA SequencingSemantic proximity Read ↗

Device for whole genome sequencing single circulating tumor cells from whole bloodSemantic proximity Read ↗

Circulating Tumor Cells: Clinically Relevant Molecular Access Based on a Novel CTC Flow CellSemantic proximity Read ↗

Development and clinical validation of a microfluidic-based platform for CTC enrichment and downstream molecular analysisSemantic proximity Read ↗

Single-Cell Analysis of Circulating Tumor Cells: Why Heterogeneity MattersSemantic proximity Read ↗

Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automationSemantic proximity Read ↗

The RareCyte® platform for next‐generation analysis of circulating tumor cellsSemantic proximity Read ↗

Future of Liquid Biopsies With Growing Technological and Bioinformatics Studies: Opportunities and Challenges in Discovering Tumor Heterogeneity With Single-Cell Level AnalysisSemantic proximity Read ↗

Fast and efficient microfluidic cell filter for isolation of circulating tumor cells from unprocessed whole blood of colorectal cancer patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.