HistAgent: an evidence-grounded agent for spatial molecular reasoning from routine histology

Abstract excerpt

<title>Abstract</title> <p>Routine hematoxylin and eosin (H&E) staining is a widely used histology test in clinical practice and biomedical research, but it does not provide direct spatial molecular information. Spatial transcriptomics (ST) provides such data while preserving the tissue context, yet its high cost, technical complexity, and limited accessibility restrict its broad application. Methods for inferrin...

Topics

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• Biomarkers, Tumor
• Deep Learning
• Gene Expression Profiling
• Machine Learning
• Neoplasms
• Phenotype
• Single-cell and spatial transcriptomics
• Transcriptome

Identifiers and source

Literature Corpus work

af053ea8-4c69-5e3f-9170-17c976590e9e

DOI

10.21203/rs.3.rs-10677502/v1