Article

RiboZAP: Custom probe design for rRNA depletion in complex metatranscriptomes

2025-11-07

Abstract excerpt

Metatranscriptomic (MetaT) sequencing provides critical insights into the gene expression and functional activity of microbial communities. However, its utility is limited by the overwhelming abundance of ribosomal RNA (rRNA), which typically represents ≥90% of total RNA [1-2]. A major obstacle to efficient MetaT analysis is the removal of highly abundant rRNA transcripts present in complex microbial communities,...

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Literature Corpus work: 200b5fe0-4172-5868-b0fc-d1a64ca6ea94
DOI: 10.1101/2025.11.07.687087

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