Article

MRSL: A phenome-wide causal discovery algorithm based on GWAS summary data

2022-06-30

Abstract excerpt

Causal discovery is a powerful tool to disclose underlying structures by analyzing purely observational data. Genetic variants can provide useful complementary information for structure learning. Here, we propose a novel algorithm MRSL (Mendelian Randomization (MR)-based Structure Learning algorithm), which combines the graph theory with univariable and multivariable MR to learn the true structure using only GWAS...

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Literature Corpus work: 1ff1ce3f-bffa-5a25-9d4a-67ce934a5bcc
DOI: 10.1101/2022.06.29.22277051

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